GHK-Cu (200mg)
GHK-Cu (Copper Peptide) is a tripeptide-copper complex studied for its anti-aging properties, collagen synthesis, and skin healing. This reference entry covers a 200 mg vial.
Reviewed by the AllPeptides.eu Editorial Team·Last reviewed: 2026-06-16
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
⚠️ For informational/educational purposes only. Not medical advice. We do not sell any products. Self-treatment carries serious risks — consult a healthcare professional. Disclaimer
Research monograph
See the full GHK-Cu encyclopedia page with mechanism, evidence tier, related variants and research context.
How It Works
GHK-Cu increases the synthesis of collagen, elastin, and proteoglycans. It also regulates metalloproteinases (MMPs) and growth factors, promoting skin regeneration and wound healing.
Quick Start
- Reconstitution: Add 10.0 mL bacteriostatic water → 20 mg/mL concentration.
- Literature-reported range: 1–2 mg subcutaneously, once daily, 5 days/week.
- Easy measurement: At 20 mg/mL, 1 mg = 5 units (0.05 mL) on a U-100 syringe.
- Storage: 2–8 °C after reconstitution.
Typical Approach (10 mL = 20 mg/mL)
Route: Subcutaneously or Topically | Frequency: Once daily (5 days/week)
| Week | Dose | Units (per injection) |
|---|---|---|
| Weeks 1–4 | 1.0 mg | 5 Units (0.05 mL) |
| Weeks 5–8 | 1.5 mg | 7.5 Units (0.07 mL) |
| Weeks 9–12 | 2.0 mg | 10 Units (0.10 mL) |
Literature reports subcutaneous administration once daily, 5 days/week, usually capped at 2 mg per day. Can also be used topically in creams.
Related compounds
Reconstitution Steps
- Draw 10.0 mL of bacteriostatic water.
- Inject slowly.
- Swirl gently (do not shake).
- Refrigerate at 2–8 °C.
Protocol Overview
- Goal: Skin anti-aging, healing, collagen synthesis.
- Schedule: 1–2 mg daily, 5 days/week × 8–12 weeks.
Dosing Protocol
- Start: 1 mg 1×/day, 5 days/week.
- Titration: 1.5 mg (Wks 5–8) → 2 mg (Wks 9–12).
- Cycle: 8–12 weeks.
- Break between cycles: A 4-week break after the cycle.
Washout & Cycle Restart
When can I restart?
A 4-week break after the cycle.
Minimum wait period: 4 weeks
Storage Instructions
- Powder: −20 °C.
- Solution: 2–8 °C, use within 28 days.
Important Notes
- The high content is considered a laboratory reference format.
- Can be used in combination with BPC-157.
- Topical use: mix into a base cream.
Potential Benefits & Side Effects
Potential Benefits:
- Increased collagen synthesis.
- Improved skin texture and elasticity.
- Anti-inflammatory action.
- High cost-effectiveness at 200 mg.
Potential Side Effects:
- Injection site reactions (redness, itching — transient).
- Local erythema or skin dryness (topical use).
- Rare allergic reaction to the copper complex.
⚠️ Serious Warnings & Long-Term Risks
The following warnings are based on published literature, FDA labels, and post-marketing surveillance. They do not constitute medical advice. Consult a healthcare professional.
Angiogenesis & tissue remodeling
GHK-Cu promotes angiogenesis, tissue regeneration, and increases collagen/elastin. Theoretical concern for enhancing existing tumors, though no clinical signal exists.
📄 Life Sci 2012References
- J Biol Chem — GHK-Cu and collagen synthesis
View Source - Oxidative Med Cell Longev — GHK multifunctionality and anti-aging
View Source
Recommended Supplements
Curcumin (Turmeric Extract)
Collagen Peptides
External Sources & Regulatory Status
Regulatory Approvals
Research-only — Cosmetic (topical) use unrestricted
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
Continue Your Research
Explore tools and guides related to this protocol.
Important Disclaimer
The content of this website is provided exclusively for informational and educational purposes within the context of research literature.
Read the full Disclaimer →