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    Ara-290: protocol variants and reconstitution resources

    Educational hub for Ara-290, grouping 1 available protocol variant with links to the exact dosage and reconstitution pages.

    What this hub covers

    This page groups the available Ara-290 protocol variants so readers can choose the exact vial-size guide without mixing formats.

    Reconstitution workflow

    Use the linked protocol pages and calculator resources to review concentration, diluent logic and unit conversions for the selected variant.

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    Ara-290

    16mg

    Ara-290 (cibinetide) is a non-erythropoietic 11-amino acid peptide derived from the helix-B domain of erythropoietin. It selectively activates the innate repair receptor (IRR), an EPOR/CD131 heterodimer, to promote anti-inflammatory and tissue-protective effects without stimulating red blood cell production. Clinical trials have shown benefits for diabetic neuropathy and sarcoidosis-associated small fiber neuropathy.

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    References

    1. IUPHAR/BPS Guide to Pharmacology — Cibinetide (ARA-290): pharmacological profile
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    2. Brines M et al. Proc Natl Acad Sci U S A 2008 — Nonerythropoietic, tissue-protective peptides derived from the tertiary structure of erythropoietin.
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    3. Molecular Medicine (2014) — ARA 290 improves metabolic control and neuropathic symptoms in type 2 DM
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    4. Molecular Medicine (2013) — ARA 290 improves sarcoidosis symptoms and increases nerve fiber density
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    5. Peptides Journal (2016) — ARA 290 relieves pain by targeting the TRPV1 channel
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