Thymosin Alpha-1 (5mg)
Thymosin Alpha-1 (Tα1) is a natural thymus peptide, approved in 30+ countries (Zadaxin®). Reconstitute with 2.5mL bacteriostatic water for 2mg/mL.
Reviewed by the AllPeptides.eu Editorial Team·Last reviewed: 2026-06-16
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
⚠️ For informational/educational purposes only. Not medical advice. We do not sell any products. Self-treatment carries serious risks — consult a healthcare professional. Disclaimer
Research monograph
See the full Thymosin Alpha-1 encyclopedia page with mechanism, evidence tier, related variants and research context.
How It Works
Tα1 activates dendritic cells, increases CD4+/CD8+ T-cells, regulates NK cells, and enhances phagocytic capacity. It acts as an immunomodulator.
Quick Start
- Typical dose: 1.6 mg subcutaneously (Zadaxin® dose)
- Frequency: 2x/week
- Storage: 2–8°C after reconstitution
Dosing Table — Thymosin Alpha-1 5mg
Route: Subcutaneous injection | Frequency: 2x weekly
| Week | Dose | Units (per injection) |
|---|---|---|
| Weeks 1–12 | 1.6 mg | 80 Units (0.80 mL) |
The classic Zadaxin® dose is 1.6mg 2x/week. Cycles are 4–12 weeks.
Related compounds
Reconstitution Steps
- Clean the vial stoppers with an alcohol wipe.
- Draw up 2.5mL of bacteriostatic water.
- Slowly inject down the side of the vial.
- Gently swirl until fully dissolved.
- Store in the refrigerator (2–8°C).
Protocol Overview
- Tα1 enhances T-cells, NK cells, and dendritic cells.
- Pharmaceutically approved in 30+ countries as Zadaxin®.
- Used for hepatitis B/C, HIV, and immune stimulation in cancer.
Dosing Protocol
- Literature dose: 1.6 mg (Zadaxin®), 2x/week.
- Cycle: 4–12 weeks, or continuous under medical supervision.
- One 5 mg vial covers 3 doses (~1.5 weeks).
- Break between cycles: After a cycle (4–12 weeks), a washout period of 4–8 weeks is recommended. Thymosin Alpha-1 regulates the immune system — the pause prevents overstimulation.
Washout & Cycle Restart
When can I restart?
After a cycle (4–12 weeks), a washout period of 4–8 weeks is recommended. Thymosin Alpha-1 regulates the immune system — the pause prevents overstimulation.
Minimum wait period: 4 weeks
Storage Instructions
- Reconstituted: 2–8°C, use within 28 days.
- Powder: -20°C.
Important Notes
- Extremely well-tolerated — rare side effects.
- Enhances immune response to vaccinations.
- Caution in autoimmune diseases.
Potential Benefits & Side Effects
Potential Benefits:
- Enhancement of T-cells and NK cells
- Antiviral action (hepatitis, HIV, HPV)
- Immune stimulation in the immunocompromised
- Adjuvant anti-cancer support
- Improved immune response to vaccines
Potential Side Effects:
- Mild redness at the injection site (rare)
- Very rare: fever
- Generally extremely well-tolerated
⚠️ Serious Warnings & Long-Term Risks
The following warnings are based on published literature, FDA labels, and post-marketing surveillance. They do not constitute medical advice. Consult a healthcare professional.
Immunostimulation — risk in autoimmune conditions
Tα1 enhances cellular immunity (CD4+, CD8+, NK). Theoretical risk of autoimmune flare (MS, RA, Lupus). Contraindicated in active autoimmune disease.
📄 Expert Opin Biol Ther 2009References
- Thymosin Alpha-1 Immunology — Garaci E, et al. Thymosin alpha 1: from bench to bedside. Ann N Y Acad Sci. 2007;1112:225-234.
View Source - Thymosin Alpha-1 Comprehensive Review — Dominari A, et al. Thymosin alpha 1: a comprehensive review of the literature. World J Virol. 2020;9(5):67-78.
View Source
Recommended Supplements
Vitamin C (High-dose)
Zinc + Selenium
External Sources & Regulatory Status
Regulatory Approvals
Zadaxin® · Hepatitis B/C, Immunodeficiency (1996)
Zadaxin® · Hepatitis B/C
Immunotherapy
Approved in 35+ countries (Zadaxin®)
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
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