MOTS-C (20mg)

MOTS-C activates AMPK (AMP-activated protein kinase), the master regulator of energy homeostasis. It improves insulin sensitivity, increases fatty acid oxidation, enhances mitochondrial function, and reduces oxidative stress.

• Reconstitution: Add 2.0 mL bacteriostatic water → 10 mg/mL concentration.
• Literature-reported range: 5 mg per injection, 2–3 times weekly (10–15 mg/week).
• Easy measurement: At 10 mg/mL, 5 mg = 50 units (0.50 mL) on a U-100 syringe.
• Storage: Lyophilized: −20 °C; reconstituted: 2–8 °C, use within 28 days.

1. Draw 2.0 mL of bacteriostatic water.
2. Inject slowly down the vial wall; avoid foaming.
3. Swirl gently until fully dissolved — do not shake.
4. Note the reconstitution date and refrigerate at 2–8 °C.

• Literature-reported scope: Metabolic homeostasis, insulin sensitivity and physical performance (mostly preclinical data).
• Literature-described schedule: 5 mg subcutaneously, 2–3 times weekly, for 4–8 weeks.
• Doses per vial: 4 × 5 mg.

• Weeks 1–2: 5 mg × 2/week (10 mg/week).
• Weeks 3–8: 5 mg × 3/week (15 mg/week).
• Literature-described break: 4 weeks after each cycle.
• There is no validated human dosing — research context only.
• Break between cycles: After a 4–8 week cycle, the literature describes a 4-week break.

• Lyophilized: −20 °C in dry, dark conditions.
• Reconstituted: 2–8 °C; use within 28 days.
• Avoid freeze-thaw cycles.

• Combine with exercise for maximal results.
• Use sterile technique.

1. Cell Metabolism — MOTS-c: a mitochondrial-derived regulator of metabolism
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2. Journal of the American Aging Association — MOTS-c and aging
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