MGF (Mechano Growth Factor) (5mg)

MGF is a splice variant of IGF-1 produced locally after mechanical stress. It activates muscle satellite cells—the stem cells for muscle regeneration. These proliferate, fuse with existing muscle fibers, and donate nuclei, increasing the potential for protein synthesis and muscle hypertrophy.

• Reconstitution: Add 2.5 mL of 0.6% acetic acid → 2.0 mg/mL. ⚠️ Acetic acid only — similar structure to IGF-1, does not dissolve properly in BAC water.
• Typical Dose: 200–400 mcg per injection, 2–3 times/wk.
• Storage: Lyophilized: −20 °C· reconstituted: 2–8 °C, use within 7–10 days.

1. ⚠️ Use 0.6% acetic acid exclusively — NOT bacteriostatic water. MGF has a hydrophobic structure similar to IGF-1.
2. Withdraw 2.5 mL of 0.6% acetic acid.
3. Slowly inject against the side wall; avoid foaming.
4. Gently swirl until fully dissolved.
5. Refrigerate at 2–8 °C; use within 7–10 days (sensitive peptide).

• Goal: Local muscle growth and repair post-workout/injury.
• Schedule: 2–3 IM injections weekly for 4–8 weeks.

• Start: 200 mcg × 2/wk.
• Titration: 300–400 mcg if well-tolerated.
• Timing: Immediately post-workout into the target muscle.
• Cycle: 4–8 weeks.
• Break between cycles: After the cycle (4–8 weeks), a 4–6 week washout period is recommended. The break prevents desensitization of IGF-1 receptors.

• Lyophilized: −20 °C.
• Reconstituted: 2–8 °C; use within 7–10 days (sensitive peptide).
• Do not freeze the reconstituted solution.

• Standard MGF has a very short half-life (~minutes).
• Inject IM locally into the target muscle immediately after exercise.
• The PEG-MGF form has an extended duration of action (~hours).

1. Endocrine Reviews (2005) — IGF-I splice variants and the role of MGF
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2. J Applied Physiology (2003) — MGF expression in human muscle
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3. Growth Hormone & IGF Research (2004) — MGF and muscle repair
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