Hexarelin (5mg)
Hexarelin is the most potent GHRP, stimulating maximal growth hormone secretion via GHS-R1a. Reconstitute with 2.5mL of bacteriostatic water for 2mg/mL.
Reviewed by the AllPeptides.eu Editorial Team·Last reviewed: 2026-06-16
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
⚠️ For informational/educational purposes only. Not medical advice. We do not sell any products. Self-treatment carries serious risks — consult a healthcare professional. Disclaimer
How It Works
Hexarelin binds to the GHS-R1a, causing large GH pulses from the pituitary gland. It also has a direct cardioprotective effect via CD36 receptors.
Quick Start
- Typical dose: 100–300mcg subcutaneously
- Frequency: 2–3x/day
- Storage: 2–8°C after reconstitution
Dosing Table — Hexarelin 5mg
Route: Subcutaneous injection | Frequency: 2–3x daily
| Week | Dose | Units (per injection) |
|---|---|---|
| 1–2 | 100mcg | 5 Units (0.05 mL) |
| 3–4 | 200mcg | 10 Units (0.10 mL) |
| 5–8 | 300mcg | 15 Units (0.15 mL) |
Desensitization develops after 4–8 weeks. Cycle: 4–8 weeks on, 4 weeks off. Increases cortisol/prolactin.
Related compounds
Reconstitution Steps
- Clean the stoppers with an alcohol wipe.
- Draw 2.5mL of bacteriostatic water.
- Slowly inject down the side of the vial.
- Gently swirl until fully dissolved.
- Store in the refrigerator (2–8°C).
Protocol Overview
- Hexarelin is a synthetic GHRP with the highest potency for GH stimulation.
- It acts via the Ghrelin receptor (GHS-R1a).
- Besides GH, it has an independent cardioprotective effect.
Dosing Protocol
- Start with 100mcg, 2x/day in a fasted state.
- Increase to 200–300mcg, 2–3x/day.
- Cycle: 4–8 weeks on, 4 weeks off (for desensitization).
- Combining with CJC-1295 significantly enhances the GH pulse.
- Break between cycles: After a cycle (8–12 weeks), a washout period of 4–8 weeks is recommended. Hexarelin can cause significant tolerance (desensitization) — the washout is critical.
Washout & Cycle Restart
When can I restart?
After a cycle (8–12 weeks), a washout period of 4–8 weeks is recommended. Hexarelin can cause significant tolerance (desensitization) — the washout is critical.
Minimum wait period: 4 weeks
Storage Instructions
- Reconstituted: 2–8°C, use within 28 days.
- Powder: -20°C.
Important Notes
- Desensitization is more pronounced than with other GHRPs.
- Increases cortisol and prolactin more than Ipamorelin/GHRP-2.
- Not recommended for long-term continuous use.
Potential Benefits & Side Effects
Potential Benefits:
- Most potent stimulation of growth hormone
- Cardioprotective action (GH-independent)
- Increased muscle mass
- Improved sleep
- Anti-inflammatory properties
Potential Side Effects:
- Increased cortisol (>GHRP-2, Ipamorelin)
- Increased prolactin
- Desensitization after 4–8 weeks
- Fluid retention / hand numbness
⚠️ Serious Warnings & Long-Term Risks
The following warnings are based on published literature, FDA labels, and post-marketing surveillance. They do not constitute medical advice. Consult a healthcare professional.
Increased cortisol & prolactin
Hexarelin, unlike ipamorelin, increases cortisol and prolactin. Possible gynecomastia with long-term use.
📄 Eur J Endocrinol 1997References
- Hexarelin GH Potency — Ghigo E, et al. Growth hormone-releasing activity of hexarelin in humans. J Clin Endocrinol Metab. 1994;78(3):693-698.
View Source - Hexarelin Cardioprotection — Bodart V, et al. CD36 mediates the cardiovascular action of hexarelin. Circ Res. 2002;90(8):907-914.
View Source
Recommended Supplements
L-Arginine + L-Ornithine
ZMA (Zinc + Magnesium + B6)
External Sources & Regulatory Status
Regulatory Approvals
GH deficiency / Cardiovascular
Phase II (development discontinued)
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
Continue Your Research
Explore tools and guides related to this protocol.
Important Disclaimer
The content of this website is provided exclusively for informational and educational purposes within the context of research literature.
Read the full Disclaimer →