GHK-Cu Oral (2 mg capsule)
GHK-Cu is a tripeptide-copper complex studied mainly topically on the skin. Use by mouth has not been studied in humans, and we found no animal study either. The 2 mg is the strength of the capsule and not a dose from any study.
Reviewed by the AllPeptides.eu Editorial Team·Last reviewed: 2026-10-31
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
⚠️ For informational/educational purposes only. Not medical advice. We do not sell any products. Self-treatment carries serious risks — consult a healthcare professional. Disclaimer
Research monograph
See the full GHK-Cu encyclopedia page with mechanism, evidence tier, related variants and research context.
How It Works
In topical and cell studies, GHK-Cu was linked to changes in collagen synthesis and gene expression (Pickart 2018). For oral administration there are no data on the mechanism.
Quick Start
- Published oral schedule: none in any of the three research sources.
- Oral data: none found in humans or animals.
- Absorption from the intestine: has not been measured.
What is published on the oral dose
Route: By mouth (per os), with no published data | Frequency: No published schedule
We checked peptidedosages.com, peptidedosage.org and peptidedosingprotocols.com on 31/10/2026, as well as PubMed. No source gives an oral schedule, so this page has no dosing table.
Related compounds
Protocol Overview
- GHK-Cu occurs naturally in human plasma and has been studied topically, in patches and in cell models (Pickart 2018).
- The topical data concern the skin and do not show what happens when the substance passes through the stomach and intestine.
- We do not know whether the complex reaches the blood intact after oral intake.
Dosing Protocol
- There is no published schedule for oral use.
Storage Instructions
- No published stability data were found for GHK-Cu capsules.
Important Notes
- Oral use has not been studied in humans.
- Findings from topical use do not carry over to oral use.
- The capsule contains copper. Copper balance after repeated intake has not been studied for this form.
- The substance has not been approved by the FDA or the EMA.
Potential Benefits & Side Effects
Potential Side Effects:
- The safety profile of oral use is unknown.
⚠️ Serious Warnings & Long-Term Risks
The following warnings are based on published literature, FDA labels, and post-marketing surveillance. They do not constitute medical advice. Consult a healthcare professional.
Angiogenesis & tissue remodeling
GHK-Cu promotes angiogenesis, tissue regeneration, and increases collagen/elastin. Theoretical concern for enhancing existing tumors, though no clinical signal exists.
📄 Life Sci 2012References
- Pickart L, Margolina A. Int J Mol Sci 2018 — Review of mainly topical and cell data. It does not support oral use.
View Source
External Sources & Regulatory Status
Regulatory Approvals
Research-only — Cosmetic (topical) use unrestricted
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
Continue Your Research
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Important Disclaimer
The content of this website is provided exclusively for informational and educational purposes within the context of research literature.
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