Crystagen (20mg)
Crystagen (Glu-Asp-Pro) is a bioregulator tripeptide studied for immunomodulation and cellular regulation. This synthetic peptide was designed to support immune function and is researched for its immunomodulatory properties. This protocol outlines a once-daily subcutaneous approach.
Reviewed by the AllPeptides.eu Editorial Team·Last reviewed: 2026-06-16
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
⚠️ For informational/educational purposes only. Not medical advice. We do not sell any products. Self-treatment carries serious risks — consult a healthcare professional. Disclaimer
How It Works
Crystagen (Glu-Asp-Pro) is a synthetic tripeptide bioregulator that acts on immune cells to support cellular regulation and immune function. Research suggests that thymic peptides and their synthetic analogs can modulate immune responses and support normal cellular function. Similar immunomodulatory peptides have been studied in clinical settings, typically administered via daily subcutaneous or intramuscular injections in short-term protocols.
Quick Start
- Reconstitution: Add 3.0 mL bacteriostatic water → 6.67 mg/mL concentration.
- Typical daily range: 1000–2000 mcg once daily (gradual titration to 2000 mcg).
- Storage: Lyophilized: refrigerator 4 °C or freezer −20 °C; after reconstitution, refrigerate at 4 °C for up to 30 days.
Typical / Gradual Approach (3 mL = 6.67 mg/mL)
Route: Subcutaneous | Frequency: Once daily
| Week | Dose | Units (per injection) |
|---|---|---|
| Week 1 | 1000 mcg (1 mg) | 15 Units (0.15 mL) |
| Week 2 | 1500 mcg (1.5 mg) | 22.5 Units (0.22 mL) |
| Weeks 3–12 | 2000 mcg (2 mg) | 30 Units (0.30 mL) |
Studies report administration once daily subcutaneously. Research protocols typically use daily subcutaneous injections for systemic immunomodulation.
Related compounds
Reconstitution Steps
- Draw 3.0 mL of bacteriostatic water.
- Inject slowly down the side of the vial; avoid foaming.
- Gently swirl/rotate until dissolved (do not shake).
- Date and refrigerate at 4 °C, protecting from light.
Protocol Overview
- Objective: Support immunomodulation and cellular regulation via bioregulatory peptide signaling.
- Schedule: Daily subcutaneous injections for 8–12 weeks (extendable to 16 weeks).
- Storage: Lyophilized in refrigerator/freezer; reconstituted in refrigerator for up to 30 days.
Dosing Protocol
- Week 1: 1000 mcg (1 mg) daily to assess tolerance.
- Week 2: 1500 mcg (1.5 mg) daily.
- Weeks 3–12: 2000 mcg (2 mg) daily (target maintenance dose).
- Frequency: Once daily (subcutaneously), at a consistent time.
- Cycle Duration: 8–12 weeks typically; optional extension to 16 weeks.
- Break between cycles: After the cycle (10–20 days), a 3–6 month pause is recommended. Khavinson bioregulatory peptides have a prolonged effect — typically 2–3 cycles per year are performed.
Washout & Cycle Restart
When can I restart?
After the cycle (10–20 days), a 3–6 month pause is recommended. Khavinson bioregulatory peptides have a prolonged effect — typically 2–3 cycles per year are performed.
Minimum wait period: 12 weeks
Storage Instructions
- Lyophilized: Store at 4 °C or −20 °C in dry, dark conditions.
- Reconstituted: Refrigerate at 4 °C; stable for approximately 30 days.
- Bacteriostatic Water: Discard multi-use vials 28 days after opening (USP standard).
- Allow vials to reach room temperature before opening.
Important Notes
- Follow aseptic technique: wash hands and clean the skin with alcohol before each injection.
Potential Benefits & Side Effects
Potential Benefits:
- May support immunomodulation and cellular regulation through bioregulatory peptide mechanisms.
- Related thymic peptides have been studied for immuno-support in various research contexts.
- Generally well-tolerated in research settings.
Potential Side Effects:
- Mild injection site reactions (redness, slight discomfort).
- Transient fatigue (rare).
- Limited human data (bioregulatory peptide).
⚠️ Serious Warnings & Long-Term Risks
The following warnings are based on published literature, FDA labels, and post-marketing surveillance. They do not constitute medical advice. Consult a healthcare professional.
Immune bioregulator — risk in autoimmune conditions
Immunostimulatory tri-peptide. Theoretical risk of autoimmune flare. No controlled studies.
📄 Khavinson VK — Bull Exp Biol MedReferences
- Thymalin Peptide: Benefits, Dosage and Administration Guide — NBINNO — Thymalin Peptide: a guide to benefits, dosage, and administration
View Source - DTS Pharmacy — Crystagen Peptide product information
View Source - Peptide Shop — THYMOGEN-10: Synthetic immune peptide
View Source - Sigma-Aldrich — Peptide handling guide
View Source - MedlinePlus — Subcutaneous injections: technique and site rotation
View Source
Recommended Supplements
Multivitamin (High-quality)
External Sources & Regulatory Status
Regulatory Approvals
Кристаген® · Immune system / Thymus (2007)
Approved in Russia (Khavinson bioregulator)
Educational information. Not medical advice, and no efficacy claim is implied. Regulatory approval is not a use recommendation by AllPeptides.eu.
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