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    PT-141 (Bremelanotide): protocol variants and reconstitution resources

    Educational hub for PT-141 (Bremelanotide), grouping 2 available protocol variants with links to the exact dosage and reconstitution pages.

    What this hub covers

    This page groups the available PT-141 (Bremelanotide) protocol variants so readers can choose the exact vial-size guide without mixing formats.

    Reconstitution workflow

    Use the linked protocol pages and calculator resources to review concentration, diluent logic and unit conversions for the selected variant.

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    Available protocol variants

    Choose the exact guide you want to view.

    PT-141 (Bremelanotide)

    5mg

    PT-141 (Bremelanotide) is a melanocortin receptor agonist, MC4R, FDA-approved (Vyleesi®, 2019) for hypoactive sexual desire disorder (HSDD) in premenopausal women. 5mg vial — reconstitute with 1mL of bacteriostatic water for a concentration of 5mg/mL (500mcg per 10 units on a U-100 syringe).

    View protocol

    PT-141 (Bremelanotide)

    10mg

    PT-141 (Bremelanotide) is an FDA-approved MC4R agonist (Vyleesi) for the treatment of hypoactive sexual desire disorder. Reconstitute with 2mL of bacteriostatic water for a concentration of 5mg/mL (500mcg per 10 units).

    View protocol

    Related research resources

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    References

    1. Kingsberg SA et al. Obstet Gynecol 2019 — Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials.
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    2. MC4R Mechanism — Molinoff PB et al. PT-141: a melanocortin agonist for sexual dysfunction. Ann N Y Acad Sci. 2003;994:96-102.
      View Source
    3. Diamond LE et al. J Sex Med 2006 — An effect on the subjective sexual response in premenopausal women with sexual arousal disorder by bremelanotide (PT-141), a melanocortin receptor agonist.
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    4. Clayton AH et al. J Womens Health (Larchmt) 2022 — Safety Profile of Bremelanotide Across the Clinical Development Program.
      View Source

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