What is Vilon? Guide to the Lysylglutamic Acid Peptide
Résumé
Vilon is a synthetic dipeptide (Lys‑Glu) from the thymic bioregulator peptide family studied for immunomodulation and cellular 'rejuvenation'. In vitro and animal studies report upregulation of the IL-2 gene, chromatin decondensation in aged lymphocytes, and lifespan extension in mice.
Propriétés de la substance
What is Vilon?
Vilon (KE, Lys-Glu) is a two-amino-acid peptide studied as a thymic bioregulator. This short peptide analogue is investigated for its ability to regulate immune system function through effects on lymphocyte gene expression.
Effects on the immune system
In laboratory studies on human lymphocytes, Vilon increased expression of the interleukin-2 (IL-2) gene, a critical cytokine for T-cell function. This suggests potential for enhancing immune response in aged cells.
Chromatin decondensation and anti-aging
Studies on aged human lymphocytes show Vilon can remodel chromatin — 'unlocking' condensed DNA regions that are silenced with aging. This heterochromatin decondensation allows reactivation of ribosomal genes.
Lifespan extension in mouse models
In longevity experiments in mice, Vilon administration was associated with increased average lifespan, although the mechanisms remain under investigation. Immunostimulation and epigenetic remodeling are considered possible mediators.
Guides associés
Foire aux questions (FAQ)
How does Vilon differ from Thymalin?
Both are thymic peptides, but Vilon (KE) is a synthetic dipeptide while Thymalin is a thymus gland extract. Vilon offers a cleaner mechanistic profile due to its exact sequence.
Is it safe for human use?
Vilon is a research compound only. It has not received regulatory approval for therapeutic use in humans.
Références & études
Avertissement
This article is exclusively educational for researchers. It does not constitute medical advice.
⚠️ À des fins informatives et éducatives uniquement. Ne constitue pas un avis médical. Nous ne vendons aucun produit. Avertissement